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An interesting concept that arises gravitates around the issue of Home as aspiration, or figment of memory, rather than reality. Andrew (Zach Braff) hypothesizes that maybe family are just people who long for "the same imaginary place." This line of thought is brought to a satisfying conclusion at the end, but I won't spoil it for you...
(Disclaimer: I didn't re-read this post before publishing it the first time round, so there was unforgivable repitition. Sorry!)